Why is it called goodpasture syndrome
Fewer than 30 percent of people with Goodpasture syndrome will suffer long-term kidney damage that requires dialysis. Quitting smoking, if you smoke, and avoiding secondhand smoke is another important step to improving your long-term outlook.
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What causes Goodpasture syndrome? How is Goodpasture syndrome diagnosed? How is Goodpasture syndrome treated? What is the long-term outlook? Chronic Kidney Failure. Respiratory Acidosis. Blood Gas Test. Anti-glomerular basement membrane disease and Goodpasture disease. Comprehensive Clinical Nephrology. Philadelphia, PA: Elsevier; chap Secondary glomerular disease. Brenner and Rector's The Kidney. URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit.
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Patient Information. Conditions Treated A-Z. Definition Anti-glomerular basement membrane diseases anti-GBM diseases is a rare disorder that can involve quickly worsening kidney failure and lung disease. Alternative Names Goodpasture syndrome; Rapidly progressive glomerulonephritis with pulmonary hemorrhage; Pulmonary renal syndrome; Glomerulonephritis - pulmonary hemorrhage Causes Anti-GBM disease is an autoimmune disorder.
Symptoms Symptoms may occur very slowly over months or even years, but they often develop very quickly over days to weeks. Loss of appetite, fatigue, and weakness are common early symptoms. Anti-GBM disease most often affects men in their 20s and women in their 60s, but it can occur at any age.
A combination of your genes and factors in the environment may put you at risk. Some genetic traits that parents pass on to their children, while uncommon, may affect the risk for developing anti-GBM disease.
For example, scientists have found a link between anti-GBM disease and human leukocyte antigen HLA , a protein on the surface of cells that plays an important role in immune response. Factors in your environment may also increase your risk of developing anti-GBM disease. They include 1. Health care professionals diagnose anti-GBM disease by reviewing your symptoms and medical history and ordering certain lab tests.
These tests often include. Plasmapheresis is usually done for 2 to 3 weeks. Once treated, anti-GBM disease rarely comes back. When it does, it is often due to ongoing exposure to chemicals that irritate the lungs. Patients who are very ill by the time they seek care may need additional treatments, such as 3. The extent of damage to the kidneys often depends on how well your kidneys were working before you started treatment.
If you already need dialysis by the time you start treatment, you are likely to stay on dialysis after treatment. Some people may need a kidney transplant.
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